UniProt Accession

 H7C2Y1_HUMAN; H7C2Y1 

Genbank Protein ID

 AC009973; AC093384; AC105380 

Genbank Nucleotide ID

  

Protein Name

 E3 ubiquitin-protein ligase TRIP12 

Protein Synonyms/Alias

  

Gene Name

 TRIP12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
4	****LMAKAIMDFRL	ubiquitination	[1]
22	PLGLPFYKWMLRQET	ubiquitination	[1]
104	FPNIELKKGGKDIPV	ubiquitination	[1]
107	IELKKGGKDIPVTIH	ubiquitination	[1]
137	KADTWDAKTLMECCR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ligase; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 187 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:GOC. 

Interpro

 IPR000569; HECT. 

Pfam

 PF00632; HECT 

SMART

 SM00119; HECTc 

PROSITE

 PS50237; HECT 

PRINTS