CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030825
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosomal protein S6 kinase delta-1 
Protein Synonyms/Alias
 cDNA FLJ61257, highly similar to Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) 
Gene Name
 RPS6KC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
354SFNTSESKVEFKAQDubiquitination[1]
377SVPVISFKDAAFDDVubiquitination[1]
462LSDPSGPKSYSITEKubiquitination[1]
572FQRDSETKGESGLVLubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 660 AA 
Protein Sequence
MRAESISSLY GKPQLDDVSQ PPGSLSSRPL WNLRSPAEEL KAFRVLGVID KVLLVMDTRT 60
EQTFILKGLR KSSEYSRNRK TIIPRCVPNM VCLHKYIISE ESVFLVLQHA EGGKLWSYIS 120
KFLNRSPEES FDIKEVKKPT LAKVHLQQPT SSPQDSSSFE SRGSDGGSML KALPLKSSLT 180
PSSQDDSNQE DDGQDSSPKW PDSGSSSEEE CTTSYLTLCN EYGQEKIEPG SLNEEPFMKT 240
EGNGVDTKAI KSFPAHLAAD SDSPSTQLRA HELKFFPNDD PEAVSSPRTS DSLSRSKNSP 300
MEFFRIDSKD SASELLGLDF GEKLYSLKSE PLKPFFTLPD GDSASRSFNT SESKVEFKAQ 360
DTISRGSDDS VPVISFKDAA FDDVSGTDEG RPDLLVNLPG ELESTREAAA MGPTKFTQTN 420
IGIIENKLLE APDVLCLRLS TEQCQAHEEK GIEELSDPSG PKSYSITEKH YAQEDPRMLF 480
VAAVDHSSSG DMSLLPSSDP KFQGLGVVES AVTANNTEES LFRICSPLSG ANEYIASTDT 540
LKTEEVLLFT DQTDDLAKEE PTSLFQRDSE TKGESGLVLE GDKEIHQIFE DLDKKLALAS 600
RFYIPEGCIQ RWAAEMVVAL DALHREGIVC RDLNPNNILL NDRGQELLQM HFFLFAVASN 660 
Gene Ontology
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom. 
Pfam
 PF00069; Pkinase 
SMART
  
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS