| Tag | Content |
|---|
| CPLM ID | CPLM-023231 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ras GTPase-activating protein-binding protein 2 |
Protein Synonyms/Alias | G3BP-2; GAP SH3 domain-binding protein 2 |
Gene Name | G3BP2 |
Gene Synonyms/Alias | KIAA0660 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 25 | QYYTLLNKAPEYLHR | ubiquitination | [1] | | 107 | NSGQPERKFMQTFVL | ubiquitination | [1] | | 337 | NTKGVGGKLPNFGFV | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Probable scaffold protein that may be involved in mRNA transport (Potential). |
Sequence Annotation | DOMAIN 11 133 NTF2.
DOMAIN 331 409 RRM.
MOD_RES 141 141 Phosphoserine.
MOD_RES 149 149 Phosphoserine.
MOD_RES 225 225 Phosphoserine (By similarity).
MOD_RES 227 227 Phosphothreonine. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; mRNA transport; Phosphoprotein; Polymorphism; Reference proteome; RNA-binding; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 482 AA |
Protein Sequence | MVMEKPSPLL VGREFVRQYY TLLNKAPEYL HRFYGRNSSY VHGGVDASGK PQEAVYGQND 60
IHHKVLSLNF SECHTKIRHV DAHATLSDGV VVQVMGLLSN SGQPERKFMQ TFVLAPEGSV 120
PNKFYVHNDM FRYEDEVFGD SEPELDEESE DEVEEEQEER QPSPEPVQEN ANSGYYEAHP 180
VTNGIEEPLE ESSHEPEPEP ESETKTEELK PQVEEKNLEE LEEKSTTPPP AEPVSLPQEP 240
PKPRVEAKPE VQSQPPRVRE QRPRERPGFP PRGPRPGRGD MEQNDSDNRR IIRYPDSHQL 300
FVGNLPHDID ENELKEFFMS FGNVVELRIN TKGVGGKLPN FGFVVFDDSE PVQRILIAKP 360
IMFRGEVRLN VEEKKTRAAR ERETRGGGDD RRDIRRNDRG PGGPRGIVGG GMMRDRDGRG 420
PPPRGGMAQK LGSGRGTGQM EGRFTGQRR 449 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. GO:0003723; F:RNA binding; NAS:UniProtKB. GO:0007253; P:cytoplasmic sequestering of NF-kappaB; NAS:UniProtKB. GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB. GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |