CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 5'-nucleotidase domain-containing protein 1 
Protein Synonyms/Alias
 Cytosolic 5'-nucleotidase II-like protein 1 
Gene Name
 Nt5dc1 
Gene Synonyms/Alias
 Nt5c2l1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
407VVYTWSSKRISTYSTubiquitination[1]
441RFSTNNSKMAGYYPLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 16 16 Nucleophile (By similarity).
 ACT_SITE 18 18 Proton donor (By similarity).
 METAL 16 16 Magnesium (By similarity).
 METAL 18 18 Magnesium; via carbonyl oxygen (By
 METAL 323 323 Magnesium (By similarity).
 MOD_RES 181 181 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 467 AA 
Protein Sequence
MAQHFSLGAC DVVGFDLDHT LCRYNLPESA RLIYNSFAQF LVKEKGYDEG LLTLTPEDWD 60
FCCKGLALDL EDGTFIKLAA DGTVLRASHG TKMMTPEALT EAFGKKEWRH CVSDKRCTSD 120
KPGVSDIPCC SGKCYFYDNY FDLPGALLCA RVVDSLTKQN RGQKTFDFWK DVVAGIQHNF 180
KMSAFKENCG FFFPEIKRNL GKYVHRCPES VRKWLRQLKD AGKITMLITS SHSDYCKLLG 240
SYILGEDFAD LFDIVITNAL KPGFFSHFPS QRPFYTLEND EEKDELPSLD KPGWYSQGNA 300
AHLYELLKKM TSKPEPKVVY FGDSMHSDIF PAHHYTNWET VLILEELQGP EMEKPEEAEP 360
LEKRGKYEAP MVKPLNTLSN KWGSYFIDSV SGRGRAEDSV VYTWSSKRIS TYSTIAIPNI 420
ESIAELPLDY KFTRFSTNNS KMAGYYPLVH HTLGSQDTDS KIISTEK 467 
Gene Ontology
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR023214; HAD-like_dom.
 IPR008380; HAD-SF_hydro_IG_5-nucl. 
Pfam
 PF05761; 5_nucleotid 
SMART
  
PROSITE
  
PRINTS