| Tag | Content |
|---|
| CPLM ID | CPLM-018594 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
Protein Synonyms/Alias | |
Gene Name | Lpgat1 |
Gene Synonyms/Alias | Fam34a |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 164 | DQQLLVLKKHLEHNY | ubiquitination | [1] | | 201 | TSQAFAKKNNLPFLT | ubiquitination | [1] | | 310 | LYQRFIEKEDLLSHF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor (By similarity). |
Sequence Annotation | MOTIF 101 106 HXXXXD motif. |
Keyword | Acyltransferase; Complete proteome; Endoplasmic reticulum; Lipid biosynthesis; Lipid metabolism; Membrane; Phospholipid biosynthesis; Phospholipid metabolism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 370 AA |
Protein Sequence | MAVTVEEAPW LGWIVAKALM RFAFMVANNL VAIPSYICYV IILQPLRVLD SKRFWYIEGL 60
MYKWLLGMVA SWGWYAGYTV MEWGEDIKAI AKDEAVMLVN HQATGDVCTL MMCLQDKGPV 120
VAQMMWLMDH IFKYTNFGIV SLIHGDFFIR QGRAYRDQQL LVLKKHLEHN YRSRDRKWIV 180
LFPEGGFLRK RRETSQAFAK KNNLPFLTHV TLPRFGATNI ILKALVARQE NGSPAGGDAR 240
GLECKSRGLQ WIIDTTIAYP KAEPIDIQTW ILGYRKPTVT HVHYRIFPIG DVPLETEDLT 300
SWLYQRFIEK EDLLSHFYKT GAFPPPQGQK EAVCREMTLS NMWIFLIQSF AFLSGYLWYH 360
IIQYFYHCLF 370 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |