CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016867
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neuron navigator 1 
Protein Synonyms/Alias
 Pore membrane and/or filament-interacting-like protein 3 
Gene Name
 Nav1 
Gene Synonyms/Alias
 Kiaa1151; Pomfil3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
210DDELLSSKAKAQKGSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May be involved in neuronal migration. 
Sequence Annotation
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 93 93 Phosphoserine (By similarity).
 MOD_RES 145 145 Phosphoserine.
 MOD_RES 162 162 Phosphothreonine (By similarity).
 MOD_RES 202 202 Phosphoserine (By similarity).
 MOD_RES 299 299 Phosphoserine (By similarity).
 MOD_RES 311 311 Phosphoserine.
 MOD_RES 365 365 Phosphoserine (By similarity).
 MOD_RES 394 394 Phosphoserine (By similarity).
 MOD_RES 455 455 Phosphoserine (By similarity).
 MOD_RES 537 537 Phosphothreonine (By similarity).
 MOD_RES 575 575 Phosphothreonine (By similarity).
 MOD_RES 752 752 Phosphoserine (By similarity).
 MOD_RES 762 762 Phosphoserine (By similarity).
 MOD_RES 810 810 Phosphoserine.
 MOD_RES 998 998 Phosphoserine (By similarity).
 MOD_RES 1004 1004 Phosphothreonine (By similarity).
 MOD_RES 1168 1168 Phosphothreonine (By similarity).
 MOD_RES 1179 1179 Phosphoserine (By similarity).
 MOD_RES 1263 1263 Phosphoserine (By similarity).
 MOD_RES 1380 1380 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Differentiation; Microtubule; Neurogenesis; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1875 AA 
Protein Sequence
MLGSSVKSVQ PEVELSGGSG SGGDEGADES RGASRKAAAA DGRGMLPKRA KAAGGSGSMA 60
KASAAELKVF KSGSVDSRVP GGLPTSNLRK QKSLTNLSFL TDSEKKLQLY EPEWSDDMAK 120
APKGLGKLGP KGRETPLMSK TLSKSEHSLF QPKGGSTGGA KTPLAPLAPS LGKPSRIPRG 180
PYAEVKPLSK APEAAVSDDG KSDDELLSSK AKAQKGSGTV PSAKGQEERA FLKVDPELVV 240
TVLGDLEQLL FSQMLDPESQ RKRTVQNVLD LRQNLEETMS SLRGSQVTHS SLEMPCYDSD 300
DANPRSVSSL SNRSSPLSWR YGQSSPRLQA GDAPSVGGSC RSEGPPAWYM HGERAHYSHT 360
MPMRSPSKLS HISRLELVES LDSDEVDLKS GYMSDSDLMG KTMTEDDDIT TGWDESSSIS 420
SGLSDASDNL SSEEFNASSS LNSLPTTPTA SRRSSTIVLR TDSEKRSLAE SGLNWFSESE 480
EKTPKKLEYD SGSLKMEPGT SKWRRERPES CDDASKGGEL KKPISLGHPG SLKKGKTPPV 540
AVTSPITHTA QSALKVAGKP EGKATDKGKL AVKNTGLQRS SSDAGRDRLS DAKKPPSGIA 600
RPSTSGSFGY KKPPPATGTA TVMQTGSSAT LSKIQKSSGI PVKPVNGRKT SLDVSNSVEP 660
GFLAPGARSN IQYRSLPRPA KSSSMSVTGR GGPRPVSSSI DPSLLSTKQG GLTPSRLKEP 720
SKVASGRSTP APVNQTDREK EKAKAKAVAL DSDNISLKSI GSPESTPKNQ ASHPPATKLA 780
ELPPTPLRAT AKSFVKPPSL ANLDKVNSNS LDLPSSSDTH ASKVPDLHAP SSSTGGPLPS 840
CFTPSPAPIL NINSASFSQG LELMSGFSVP KETRMYPKLS GLHRSMESLQ MPMSLPSAFP 900
SSAPIPTPPT APSEEDTEEL PWSGSPRAGQ LDSSQRDRNT LPKKGLRYQL QSQEETKERR 960
HSHTAGGLPE SDDQAELPSP PALSMSLSAK GQLTNIVSPT AATTPRITRS NSIPTHEAAF 1020
ELYSGSQMGS TLSLAERPKG MIRSGSFRDP TDDVHGSVLS LASSASSTYS SAEERMQSEQ 1080
IRKLRRELES SQEKVATLTS QLSANANLVA AFEQSLVNMT SRLRHLAETA EEKDTELLDL 1140
RETIDFLKKK NSEAQAVIQG ALNASEATPK ELRIKRQNSS DSISSLNSIT SHSSIGSSKD 1200
ADAKKKKKKS WVYELRSSFN KAFSIKKGPK SASSYSDIEE IATPDSSAPS SPKLQHGSTE 1260
TASPSIKSST SSSVGTEVTE TPAHSVPHTR LFQANEEEEP EKKEVSELRS ELWEKEMKLT 1320
DIRLEALNSA HQLDQLRETM HNMQLEVDLL KAENDRLKVA PGPSSGCTPG QVPGSSALSS 1380
PRRSLGLALS HPFSPSLTDT DLSPMDGIST CGSKEEVTLR VVVRMPPQHI IKGDLKQQEF 1440
FLGCSKVSGK VDWKMLDEAV FQVFKDYISK MDPASTLGLS TESIHGYSLS HVKRVLDAEP 1500
PEMPPCRRGV NNISVALKGL KEKCVDSLVF ETLIPKPMMQ HYISLLLKHR RLVLSGPSGT 1560
GKTYLTNRLA EYLVERSGRE VTDGIVSTFN MHQQSCKDLQ LYLSNLANQI DRETGIGDVP 1620
LVILLDDLSE AGSISELVNG ALTCKYHKCP YIIGTTNQPV KMTPNHGLHL SFRMLTFSNN 1680
VEPANGFLVR YLRRKLVESD SDVNANKEEL LRVLDWVPKL WYHLHTFLEK HSTSDFLIGP 1740
CFFLSCPIGI EDFRTWFIDL WNNSIIPYLQ EGAKDGIKVH GQKAAWEDPV EWVRDTLPWP 1800
SAQQDQSKLY HLPPPSVGPH STASPPEDRT VKDSTPNSLD SDPLMAMLLK LQEAANYIES 1860
PDRETILDPN LQATL 1875 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0015630; C:microtubule cytoskeleton; IDA:MGI.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0001578; P:microtubule bundle formation; IDA:MGI.
 GO:0001764; P:neuron migration; IMP:MGI. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
 SM00382; AAA 
PROSITE
  
PRINTS