CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036483
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein-L-isoaspartate O-methyltransferase 
Protein Synonyms/Alias
  
Gene Name
 Pcmt1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
62VCFAMAWKSGGASHSacetylation[1]
264QDGSVKMKPLMGVIYubiquitination[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 286 AA 
Protein Sequence
MPGARIGGSG SDGSNSGRSS GDTSGAVTVW EVVSLLGKLL GTVAALKVVL YLLRVCFAMA 60
WKSGGASHSE LIHNLRKNGI IKTDKVFEVM LATDRSHYAK SNPYMDSPQS IGFQATISAP 120
HMHAYALELL FDQLHEGAKA LDVGSGSGIL TACFARMVGN SGKVIGIDHI KELVDDSITN 180
VKKDDPMLLS SGRVRLVVGD GRMGYAEEAP YDAIHVGAAA PVVPQALIDQ LKPGGRLILP 240
VGPAGGNQML EQYDKLQDGS VKMKPLMGVI YVPLTDKEKQ WSRDEL 286 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IDA:MGI. 
Interpro
 IPR000682; PCMT. 
Pfam
 PF01135; PCMT 
SMART
  
PROSITE
 PS01279; PCMT 
PRINTS