CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043372
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Katanin p80 WD40 repeat-containing subunit B1 
Protein Synonyms/Alias
  
Gene Name
 KATNB1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
100VWDLEAAKILRTLMGubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 208 AA 
Protein Sequence
MIQDRDRCAQ AAAVAAVEEI VAHASNVSSL VLGKASGRLL ATGGDDCRVN LWSINKPNCI 60
MSLTGHTSPV ESVRLNTPEE LIVAGSQSGS IRVWDLEAAK ILRTLMGHKA NICSLDFHPY 120
GEFVASGSQD TNIKLWDIRR KGCVFRYRGH SQAVRCLRFS PDGKWLASAA DDHTVKLWDL 180
TAGKMMSEFP GHTGPVNVVE FHPNEYLL 208 
Gene Ontology
 GO:0008352; C:katanin complex; IEA:InterPro.
 GO:0051013; P:microtubule severing; IEA:InterPro. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR026962; Katanin_bsu1.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.