| Tag | Content |
|---|
| CPLM ID | CPLM-003249 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Hydrogenase isoenzymes nickel incorporation protein HypB |
Protein Synonyms/Alias | |
Gene Name | hypB |
Gene Synonyms/Alias | b2727; JW2697 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 221 | SVTEGEDKPLKYPHM | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Required for the maturation of the three [NiFe]hydrogenases. Exhibits a low intrinsic GTPase activity. The GTP hydrolysis catalyzed by HypB is an integral process in the incorporation of nickel into hydrogenases. |
Sequence Annotation | |
Keyword | Complete proteome; Direct protein sequencing; GTP-binding; Hydrolase; Metal-binding; Nickel; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 290 AA |
Protein Sequence | MCTTCGCGEG NLYIEGDEHN PHSAFRSAPF APAARPKMKI TGIKAPEFTP SQTEEGDLHY 60
GHGEAGTHAP GMSQRRMLEV EIDVLDKNNR LAERNRARFA ARKQLVLNLV SSPGSGKTTL 120
LTETLMRLKD SVPCAVIEGD QQTVNDAARI RATGTPAIQV NTGKGCHLDA QMIADAAPRL 180
PLDDNGILFI ENVGNLVCPA SFDLGEKHKV AVLSVTEGED KPLKYPHMFA AASLMLLNKV 240
DLLPYLNFDV EKCIACAREV NPEIEIILIS ATSGEGMDQW LNWLETQRCA 290 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |