CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010011
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp 
Protein Synonyms/Alias
 t(6)A37 threonylcarbamoyladenosine biosynthesis protein 
Gene Name
 gcp 
Gene Synonyms/Alias
 MPN_059; MP095 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
207RPSTKWTKFSYSGLKacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 319 AA 
Protein Sequence
MEQPLCILGI ETTCDDTSIG VITESKVQAH IVLSSAKLHA QTGGVVPEVA ARSHEQNLLK 60
ALQQSGVVLE QITHIAYAAN PGLPGCLHVG ATFARSLSFL LDKPLLPINH LYAHIFSALI 120
DQDINQLKLP ALGLVVSGGH TAIYLIKSLF DLELIAETSD DAIGEVYDKV GRAMGFPYPA 180
GPQLDSLFQP ELVKSHYFFR PSTKWTKFSY SGLKSQCFTK IKQLRERKGF NPQTHDWNEF 240
ASNFQATIID HYINHVKDAI QQHQPQMLLL GGGVSANKYL REQVTQLQLP YLIAPLKYTS 300
DNGAMIGFYA NLLINGKNN 319 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0070526; P:threonylcarbamoyladenosine biosynthetic process; IEA:HAMAP. 
Interpro
 IPR000905; Gcp-like_dom.
 IPR017861; KAE1/YgjD.
 IPR017860; Peptidase_M22_CS.
 IPR022450; T6A_Gcp_(YgjD). 
Pfam
 PF00814; Peptidase_M22 
SMART
  
PROSITE
 PS01016; GLYCOPROTEASE 
PRINTS
 PR00789; OSIALOPTASE.