UniProt Accession

 CYTB_RAT; P01041 

Genbank Protein ID

 X54737; D10607; BC084725 

Genbank Nucleotide ID

 CAA38534.1; BAA01462.1; AAH84725.1 

Protein Name

 Cystatin-B 

Protein Synonyms/Alias

 Cystatin-beta; Liver thiol proteinase inhibitor; Stefin-B 

Gene Name

 Cstb 

Gene Synonyms/Alias

 Cst6 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
30	VKSQLEEKANQKFDV	acetylation	[1]
34	LEEKANQKFDVFKAI	acetylation	[1]
39	NQKFDVFKAISFRRQ	acetylation	[1]
78	EPLPHENKPLTLSSY	acetylation	[1]
89	LSSYQTDKEKHDELT	acetylation	[1]
91	SYQTDKEKHDELTYF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 This is an intracellular thiol proteinase inhibitor. 

Sequence Annotation

 MOTIF 46 50 Secondary area of contact.
 MOD_RES 1 1 N-acetylmethionine.  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Protease inhibitor; Reference proteome; Thiol protease inhibitor. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 98 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:RGD.
 GO:0008344; P:adult locomotory behavior; IEA:Compara.
 GO:0042981; P:regulation of apoptotic process; IEP:RGD. 

Interpro

 IPR000010; Prot_inh_cystat.
 IPR018073; Prot_inh_cystat_CS.
 IPR001713; Prot_inh_stefinA. 

Pfam

 PF00031; Cystatin 

SMART

 SM00043; CY 

PROSITE

 PS00287; CYSTATIN 

PRINTS

 PR00295; STEFINA.