CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029177
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HCG2019817, isoform CRA_b 
Protein Synonyms/Alias
 RanBP-type and C3HC4-type zinc finger-containing protein 1 
Gene Name
 RBCK1 
Gene Synonyms/Alias
 hCG_2019817 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
165NTYSCSGKLLEREIKubiquitination[1, 2]
172KLLEREIKALLTPEDubiquitination[1, 2, 3]
242IHEQMNCKEYQEDLAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
MGCGRMGTVP TSICCQPATP PSTLRSCSGS GSCGCWKIWA SRTSRCSRGA LWSQAPQSPG 60
SPRNPDGGSQ MQCLSPHRWA GSAPGAPSST SPRGLAVRCA AGRAPRPTRS PPHTSPTRRS 120
ERAWRARRRR CVSTSRECLQ GTIRNSQEAE VSCPFIDNTY SCSGKLLERE IKALLTPEDY 180
QRFLDLGISI AENRSAFSYH CKTPDCKGWC FFEDDVNEFT CPVCFHVNCL LCKAIHEQMN 240
CKEYQEDLAL RAQNDVAARQ TTEMLKVMLQ QGEAMRCPQC QIVVQKKDGC DWIRCTVCHT 300
EICWVTKGPR WGPGGPGDTS GGCRCRVNGI PCHPSCQNCH 340 
Gene Ontology
 GO:0071797; C:LUBAC complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:GOC.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR026261; RBCK1.
 IPR002867; Znf_C6HC. 
Pfam
 PF01485; IBR 
SMART
  
PROSITE
  
PRINTS