CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029470
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HCG2033702, isoform CRA_a 
Protein Synonyms/Alias
 Suppressor of SWI4 1 homolog 
Gene Name
 PPAN 
Gene Synonyms/Alias
 hCG_2033702 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
45TETNVYFKLMRLPGGubiquitination[1]
125KVNLNTIKRCLLIDYubiquitination[2]
147DFRHYSIKVVPVGASubiquitination[2]
159GASRGMKKLLQEKFPubiquitination[1]
164MKKLLQEKFPNMSRLubiquitination[1, 2, 3, 4]
241QEGVGEGKVMFHSFVubiquitination[2, 4]
264AILEAKEKKLRLKAQubiquitination[2]
382RGRLCDQKFPKTKDKubiquitination[4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 420 AA 
Protein Sequence
MEPLTASRLQ VRKKNSLKDC VAVAGPLGVT HFLILSKTET NVYFKLMRLP GGPTLTFQVK 60
KYSLVRDVVS SLRRHRMHEQ QFAHPPLLVL NSFGPHGMHV KLMATMFQNL FPSINVHKVN 120
LNTIKRCLLI DYNPDSQELD FRHYSIKVVP VGASRGMKKL LQEKFPNMSR LQDISELLAT 180
GAGLSESEAE PDGDHNITEL PQAVAGRGNM RAQQSAVRLT EIGPRMTLQL IKVQEGVGEG 240
KVMFHSFVSK TEEELQAILE AKEKKLRLKA QRQAQQAQNV QRKQEQREAH RKKSLEGMKK 300
ARVGGSDEEA SGIPSRTASL ELGEDDDEQE DDDIEYFCQA VGEAPSEDLF PEAKQKRLAK 360
SPGRKRKRWE MDRGRGRLCD QKFPKTKDKS QGAQARRGPR GASRDGGRGR GRGRPGKRVA 420 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR007109; Brix. 
Pfam
 PF04427; Brix 
SMART
 SM00879; Brix 
PROSITE
 PS50833; BRIX 
PRINTS