CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027112
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MHC class II antigen 
Protein Synonyms/Alias
  
Gene Name
 HLA-DQA1/DRA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
76WRWPEFSKFGGFDPQubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Immunity; Membrane; MHC II; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 255 AA 
Protein Sequence
MILNKALLLG ALALTTVMSP CGGEDIVADH VASCGVNLYQ FYGPSGQYTH EFDGDEEFYV 60
DLERKETAWR WPEFSKFGGF DPQGALRNMA VAKHNLNIMI KRYNSTAATN VPPEVTVLTN 120
SPVELREPNV LICFIDKFTP PVVNVTWLRN GKPVTTGVSE TVFLPREDHL FRKFHYLPFL 180
PSTEDVYDCR VEHWGLDEPL LKHWEFDAPS PLPETTENVV CALGLTVGLV GIIIGTIFII 240
KGVRKSNAAE RRGPL 255 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR001003; MHC_II_a_N. 
Pfam
 PF07654; C1-set
 PF00993; MHC_II_alpha 
SMART
 SM00407; IGc1
 SM00920; MHC_II_alpha 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS