UniProt Accession

 STX16_HUMAN; O14662; A6NK32; A6NN69; A8MPP0; B7ZBN1; B7ZBN2; B7ZBN3; E1P5M0; E1P607; O14661; O14663; O60517; Q5W084; Q5W086; Q5W087; Q5XKI6; Q6GMS8; Q9H0Z0; Q9H1T7; Q9H1T8; Q9UIX5 

Genbank Protein ID

 AF008936; AF008935; AF008937; AF038897; AL139349; AL050327; AL139349; AL050327; AL139349; AL050327; AL050327; AL139349; AL050327; AL139349; AL050327; AL139349; AL050327; AL139349; AL139349; AL050327; CH471077; CH471077; CH471077; CH471077; CH471077; BC019042; BC073876; BX396221 

Genbank Nucleotide ID

 AAB69283.1; AAB69282.1; AAB69284.1; AAC05647.1; CAX14989.1; CAX14989.1; CAX14990.1; CAX14990.1; CAX14991.1; CAX14991.1; CAI23277.1; CAI23277.1; CAI23278.1; CAI23278.1; CAI23279.1; CAI23279.1; CAM28341.1; CAM28341.1; CAX14992.1; CAX14992.1; EAW75481.1; EAW75482.1; EAW75484.1; EAW75485.1; EAW75486.1; AAH19042.1; AAH73876.1 

Protein Name

 Syntaxin-16 

Protein Synonyms/Alias

 Syn16 

Gene Name

 STX16 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
185	HAQSGYLKRMKNREE	ubiquitination	[1]
301	QYQKKNRKMLVILIL	ubiquitination	[2]

Reference

 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. 

Sequence Annotation

 DOMAIN 230 292 t-SNARE coiled-coil homology.
 MOD_RES 35 35 Phosphoserine (By similarity).  

Keyword

 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 325 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; TAS:ProtInc.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0031201; C:SNARE complex; TAS:HGNC.
 GO:0005484; F:SNAP receptor activity; IDA:HGNC.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB. 

Interpro

 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 

Pfam

 PF05739; SNARE
 PF00804; Syntaxin 

SMART

 SM00397; t_SNARE 

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS