CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025359
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hydroxyacid oxidase 1, liver 
Protein Synonyms/Alias
  
Gene Name
 Hao1 
Gene Synonyms/Alias
 mCG_9861 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
21HVRSVLQKSVYDYYRubiquitination[1]
184LPPQLRMKNFETNDLubiquitination[1]
236TSLPIVVKGILRGDDubiquitination[1]
249DDAKEAVKHGVDGILubiquitination[1]
302RKGTDVLKALALGAKubiquitination[1]
337QDVLEILKEEFRLAMubiquitination[1]
357QNVKVIDKTLVRKNPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MLPRLVCISD YEQHVRSVLQ KSVYDYYRSG ANDQETLADN IQAFSRWKLY PRMLRNVADI 60
DLSTSVLGQR VSMPICVGAT AMQCMAHVDG ELATVRACQT MGTGMMLSSW ATSSIEEVAE 120
AGPEALRWMQ LYIYKDREIS RQIVKRAEKQ GYKAIFVTVD TPYLGNRIDD VRNRFKLPPQ 180
LRMKNFETND LAFSPKGNFG DNSGLAEYVA QAIDPSLSWD DITWLRRLTS LPIVVKGILR 240
GDDAKEAVKH GVDGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV 300
LKALALGAKA VFVGRPIIWG LAFQGEKGVQ DVLEILKEEF RLAMALSGCQ NVKVIDKTLV 360
RKNPLAVSKI 370 
Gene Ontology
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0003973; F:(S)-2-hydroxy-acid oxidase activity; IDA:MGI.
 GO:0010181; F:FMN binding; IEA:Compara.
 GO:0008891; F:glycolate oxidase activity; IEA:Compara.
 GO:0001561; P:fatty acid alpha-oxidation; IEA:Compara.
 GO:0006979; P:response to oxidative stress; IEA:Compara. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR012133; Alpha-hydoxy_acid_DH_FMN.
 IPR000262; FMN-dep_DH.
 IPR008259; FMN_hydac_DH_AS. 
Pfam
 PF01070; FMN_dh 
SMART
  
PROSITE
 PS00557; FMN_HYDROXY_ACID_DH_1
 PS51349; FMN_HYDROXY_ACID_DH_2 
PRINTS