CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038175
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone deacetylase 7 
Protein Synonyms/Alias
  
Gene Name
 Hdac7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
503RLKLDNGKLTGLLAQacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 851 AA 
Protein Sequence
MDLRVGQRPT VEPPPEPALL TLQHPQRLHR HLFLAGLHQQ QRSAEPMRLS MDPPMPELQG 60
GQQEQELRQL LNKDKSKRSA VASSVVKQKL AEVILKKQQA ALERTVHPSS PSIPYRTLEP 120
LDTEGAARSV LSSFLPPVPS LPTEPPEHFP LRKTVSEPNL KLRYKPKKSL ERRKNPLLRK 180
ESAPPSLRRR PAETLGDSSP SSSSTPASGC SSPNDSEHGP NPALGSEADG DRRTHSTLGP 240
RGPVLGNPHA PLFLHHGLEP EAGGTLPSRL QPILLLDPSV SHAPLWTVPG LGPLPFHFAQ 300
PLLTTERLSG SGLHRPLNRT RSEPLPPSAT ASPLLAPLQP RQDRLKPHVQ LIKVPPWEQQ 360
HLAGRLSQGS PGDSVLIPLA QVGHRPLSRT QSSPAAPVSL LSPEPTCQTQ VLNSSETPAT 420
GLVYDSVMLK HQCSCGDNSK HPEHAGRIQS IWSRLQERGL RSQCECLRGR KASLEELQSV 480
HSERHVLLYG TNPLSRLKLD NGKLTGLLAQ RTFVMLPCGG VGVDTDTIWN ELHSSNAARW 540
AAGSVTDLAF KVASRELKNG FAVVRPPGHH ADHSTAMGFC FFNSVAIACR QLQQHGKASK 600
ILIVDWDVHH GNGTQQTFYQ DPSVLYISLH RHDDGNFFPG SGAVDEVGTG SGEGFNVNVA 660
WAGGLDPPMG DPEYLAAFRI VVMPIAREFA PDLVLVSAGF DAAEGHPAPL GGYHVSAKCF 720
GYMTQQLMNL AGGAVVLALE GGHDLTAICD ASEACVAALL GNKVDPLSEE SWKQKPNLSA 780
IRSLEAVVRV HRKYWGCMQR LASCPDSWLP RVPGADAEVE AVTALASLSV GILAEDRPSE 840
RLVEEEEPMN L 851 
Gene Ontology
 GO:0000118; C:histone deacetylase complex; IEA:InterPro.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0004407; F:histone deacetylase activity; IEA:InterPro.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0007043; P:cell-cell junction assembly; IMP:MGI.
 GO:0016575; P:histone deacetylation; IEA:GOC.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0001570; P:vasculogenesis; IMP:MGI. 
Interpro
 IPR000286; His_deacetylse.
 IPR023801; His_deacetylse_dom.
 IPR017320; Histone_deAcase_II_euk. 
Pfam
 PF00850; Hist_deacetyl 
SMART
  
PROSITE
  
PRINTS
 PR01270; HDASUPER.