CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034231
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Chchd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
63SVSDEDLKRRVAEELubiquitination[1]
128KHLDIEDKARQLEEKacetylation[2]
147RKQDAFYKEQLARLEacetylation[3]
162ERSSEFYKVTTEEYQacetylation[3, 4]
162ERSSEFYKVTTEEYQubiquitination[1]
178AAEEVEAKFKRYEYHacetylation[3, 4]
178AAEEVEAKFKRYEYHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [3] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [4] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 192 AA 
Protein Sequence
MGGTASTRRV TFEADENENI TVVKGIRLSE NVIDRMKESS PSGSKSQRYS SVYGASVSDE 60
DLKRRVAEEL ALEQAKKESE HQRRLKQARD LERERAAANE QLTRAVLRER ISSEEERMKA 120
KHLDIEDKAR QLEEKDRVMR KQDAFYKEQL ARLEERSSEF YKVTTEEYQK AAEEVEAKFK 180
RYEYHPVCAD LQ 192 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI. 
Interpro
 IPR007964; DUF737. 
Pfam
 PF05300; DUF737 
SMART
  
PROSITE
  
PRINTS