| Tag | Content |
|---|
| CPLM ID | CPLM-022240 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kelch repeat and BTB domain-containing protein 4 |
Protein Synonyms/Alias | BTB and kelch domain-containing protein 4 |
Gene Name | KBTBD4 |
Gene Synonyms/Alias | BKLHD4 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 183 | PELYTAAKHCAKTHL | ubiquitination | [1] | | 187 | TAAKHCAKTHLAQLQ | ubiquitination | [1] | | 248 | ESLRTSLKEIGENVH | ubiquitination | [1] | | 261 | VHIYLIGKESSRTHS | ubiquitination | [1] | | 316 | SIPRRMWKCNNATVD | ubiquitination | [1] | | 345 | TLVSVPGKDAIYSLG | ubiquitination | [1] | | 425 | CFDTETDKCHVKPYV | ubiquitination | [1] | | 429 | ETDKCHVKPYVLPFA | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 45 112 BTB.
DOMAIN 147 239 BACK.
REPEAT 239 285 Kelch 1.
REPEAT 286 328 Kelch 2.
REPEAT 331 378 Kelch 3.
REPEAT 380 430 Kelch 4.
REPEAT 432 481 Kelch 5. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Kelch repeat; Polymorphism; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 518 AA |
Protein Sequence | MKGGNADSWQ REKLASMESP EEPGASMDEN YFVNYTFKDR SHSGRVAQGI MKLCLEEELF 60
ADVTISVEGR EFQLHRLVLS AQSCFFRSMF TSNLKEAHNR VIVLQDVSES VFQLLVDYIY 120
HGTVKLRAEE LQEIYEVSDM YQLTSLFEEC SRFLARTVQV GNCLQVMWLA DRHSDPELYT 180
AAKHCAKTHL AQLQNTEEFL HLPHRLLTDI ISDGVPCSQN PTEAIEAWIN FNKEEREAFA 240
ESLRTSLKEI GENVHIYLIG KESSRTHSLA VSLHCAEDDS ISVSGQNSLC HQITAACKHG 300
GDLYVVGGSI PRRMWKCNNA TVDWEWCAPL PRDRLQHTLV SVPGKDAIYS LGGKTLQDTL 360
SNAVIYYRVG DNVWTETTQL EVAVSGAAGA NLNGIIYLLG GEENDLDFFT KPSRLIQCFD 420
TETDKCHVKP YVLPFAGRMH AAVHKDLVFI VAEGDSLVCY NPLLDSFTRL CLPEAWSSAP 480
SLWKIASCNG SIYVFRDRYK KGDANTYKLD PATSAVTVTR GIKVLLTNLQ FVLA 534 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |