| Tag | Content |
|---|
| CPLM ID | CPLM-016210 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 589 |
Protein Synonyms/Alias | Stem cell zinc finger protein 1 |
Gene Name | ZNF589 |
Gene Synonyms/Alias | SZF1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 274 | QRTHTGEKPYVCGEC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor. |
Sequence Annotation | DOMAIN 35 108 KRAB.
ZN_FING 248 270 C2H2-type 1.
ZN_FING 276 298 C2H2-type 2.
ZN_FING 304 326 C2H2-type 3.
ZN_FING 332 354 C2H2-type 4.
MOD_RES 190 190 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 364 AA |
Protein Sequence | MWAPREQLLG WTAEALPAKD SAWPWEEKPR YLGPVTFEDV AVLFTEAEWK RLSLEQRNLY 60
KEVMLENLRN LVSLAESKPE VHTCPSCPLA FGSQQFLSQD ELHNHPIPGF HAGNQLHPGN 120
PCPEDQPQSQ HPSDKNHRGA EAEDQRVEGG VRPLFWSTNE RGALVGFSSL FQRPPISSWG 180
GNRILEIQLS PAQNASSEEV DRISKRAETP GFGAVTFGEC ALAFNQKSNL FRQKAVTAEK 240
SSDKRQSQVC RECGRGFSRK SQLIIHQRTH TGEKPYVCGE CGRGFIVESV LRNHLSTHSG 300
EKPYVCSHCG RGFSCKPYLI RHQRTHTREK SFMCTVCGRG FREKSELIKH QRIHTGDKPY 360
VCRD 364 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |