CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Non-histone chromosomal protein HMG-17 
Protein Synonyms/Alias
  
Gene Name
 Hmgn2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
17GEAEGDAKGDKTKVKacetylation[1]
37RSARLSAKPAPPKPEacetylation[2, 3]
42SAKPAPPKPEPKPKKacetylation[3]
54PKKAPAKKGEKVPKGacetylation[3]
57APAKKGEKVPKGKKGacetylation[1, 3]
70KGKADAGKDANNPAEacetylation[4]
88AKTDQAQKAEGAGDAacetylation[3]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [4] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 96 AA 
Protein Sequence
MATAPGAASG EAEGDAKGDK TKVKDEPQRR SARLSAKPAP PKPEPKPKKA PAKKGEKVPK 60
GKKGKADAGK DANNPAENGD AKTDQAQKAE GAGDAK 96 
Gene Ontology
 GO:0000785; C:chromatin; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0031492; F:nucleosomal DNA binding; IEA:InterPro. 
Interpro
 IPR000079; HMGN_fam. 
Pfam
 PF01101; HMG14_17 
SMART
 SM00527; HMG17 
PROSITE
 PS00355; HMG14_17 
PRINTS
 PR00925; NONHISHMG17.