UniProt Accession

 ATPG_DROME; O01666; A4V3L6; Q0KHZ7; Q9VAH8 

Genbank Protein ID

 AE014297; AE014297; AY113454; Y12701 

Genbank Nucleotide ID

 AAN14185.1; AAN14186.1; AAM29459.1; CAA73233.1 

Protein Name

 ATP synthase subunit gamma, mitochondrial 

Protein Synonyms/Alias

 F-ATPase gamma subunit 

Gene Name

 ATPsyn-gamma 

Gene Synonyms/Alias

 CG7610 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
56	MKMVSAAKYARAERD	acetylation	[1]
88	TEIQPDEKAEPKKLL	acetylation	[1]
128	AQDEANTKVFCVGDK	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. 

Sequence Annotation

  

Keyword

 ATP synthesis; CF(1); Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 297 AA 

Protein Sequence

Gene Ontology

 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
 GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase. 

Interpro

 IPR000131; ATPase_F1-cplx_gsu.
 IPR023632; ATPase_F1_gsu_CS.
 IPR023633; ATPase_F1_gsu_dom. 

Pfam

 PF00231; ATP-synt 

SMART

  

PROSITE

 PS00153; ATPASE_GAMMA 

PRINTS

 PR00126; ATPASEGAMMA.