Tag | Content |
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CPLM ID | CPLM-016571 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Large neutral amino acids transporter small subunit 3 |
Protein Synonyms/Alias | L-type amino acid transporter 3; Solute carrier family 43 member 1 |
Gene Name | Slc43a1 |
Gene Synonyms/Alias | Lat3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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6 | **MAPTLKQAYRRRW | ubiquitination | [1] | 555 | TNLVDPQKVLNTSKV | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine (By similarity). |
Sequence Annotation | MOD_RES 265 265 Phosphoserine. CARBOHYD 54 54 N-linked (GlcNAc...) (Potential). CARBOHYD 57 57 N-linked (GlcNAc...). CARBOHYD 396 396 N-linked (GlcNAc...) (Potential). CARBOHYD 558 558 N-linked (GlcNAc...) (Potential). |
Keyword | Amino-acid transport; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 564 AA |
Protein Sequence | MAPTLKQAYR RRWWMACTAV VENLFFSAVL LGWASLLIML KKEGFYSSLC PAENRTNTTQ 60 DEQHQWTSCD QQEKMLNLGF TIGSFLLSAT TLPLGILMDR FGPRPLRLVG SACFAASCTL 120 MALASRDTEV LSPLIFLALS LNGFAGICLT FTSLTLPNMF GNLRSTFMAL MIGSYASSAI 180 TFPGIKLIYD AGVPFTVIMF TWSGLACLIF LNCALNWPAE AFPAPEEVDY TKKIKLIGLA 240 LDHKVTGDRF YTHVTIVGQR LSQKSPSLEE GADAFISSPD IPGTSEETPE KSVPFRKSLC 300 SPIFLWSLVT MGMTQLRVIF YMGAMNKILE FIVTGGKERE TNEQRQKVEE TVEFYSSIFG 360 VMQLLCLLTC PLIGYIMDWR IKDCVDAPTE GTLNENASFG DARDGASTKF TRPRYRKVQK 420 LTNAINAFTL TNILLVGFGI ACLIKNLHLQ LLAFVLHTIV RGFFHSACGG LYAAVFPSNH 480 FGTLTGLQSL ISAVFALLQQ LLFMAMVGPL HGDPFWVNLG LLLLSFLGFL LPSYLYYYRS 540 RLQREYATNL VDPQKVLNTS KVAT 564 |
Gene Ontology | GO:0005887; C:integral to plasma membrane; IEA:InterPro. GO:0015179; F:L-amino acid transmembrane transporter activity; IDA:MGI. GO:0015175; F:neutral amino acid transmembrane transporter activity; ISS:UniProtKB. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |