UniProt Accession

 STX18_HUMAN; Q9P2W9; Q596L3; Q5TZP5 

Genbank Protein ID

 AB028741; AY453396; BT007150; BT020135; BC014613 

Genbank Nucleotide ID

 BAA95213.1; AAS47513.1; AAP35814.1; AAV38937.1; AAH14613.1 

Protein Name

 Syntaxin-18 

Protein Synonyms/Alias

 Cell growth-inhibiting gene 9 protein 

Gene Name

 STX18 

Gene Synonyms/Alias

 GIG9 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
21	KTVKTRNKALGVAVG	ubiquitination	[1]
62	EVISHIGKLRDFLLE	ubiquitination	[1]
72	DFLLEHRKDYINAYS	ubiquitination	[1]
143	DFIEDYLKRVCKLYS	ubiquitination	[1]
168	VDKKRLSKLEPEPNT	ubiquitination	[1]
296	VGATENIKEGNEDIR	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. 

Sequence Annotation

 DOMAIN 243 305 t-SNARE coiled-coil homology.  

Keyword

 Coiled coil; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane; Polymorphism; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 335 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 

Interpro

 IPR019529; Syntaxin-18_N.
 IPR006012; Syntaxin/epimorphin_CS. 

Pfam

 PF10496; Syntaxin-18_N 

SMART

  

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS