| Tag | Content |
|---|
| CPLM ID | CPLM-007329 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein N-terminal amidase |
Protein Synonyms/Alias | NT-amidase |
Gene Name | NTA1 |
Gene Synonyms/Alias | YJR062C; J1742 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 319 | KSRINWFKNSSLIES | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Deamidates N-terminal Asn and Gln. Component of a targeting complex in the N-end rule pathway. |
Sequence Annotation | DOMAIN 19 319 CN hydrolase.
ACT_SITE 63 63 Proton acceptor (Potential).
ACT_SITE 136 136 Potential.
ACT_SITE 187 187 Nucleophile (By similarity). |
Keyword | Complete proteome; Hydrolase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 457 AA |
Protein Sequence | MLIDAIHGAK MSTKLLVSLK VLVIQLNPQI GQVDQTIKRT WSILDKVTKS ATYVKPDIIL 60
FPEFALTGYS FHARKDILPY VTKKDEGPSF ELAKSISEKF QCYTIIGYPE DDDEQKLYNS 120
ALVVNPQGEQ IFNYRKTFLY DTEMNWDCEE NPEGFQTFPM DFSKCAKLSN EDSYNRDVTL 180
KASIGICMDL SPYKFMAPFN HFEFSSFCVD NNVELILCPM AWLNSTSITD KQTLHNNSLL 240
EAAKNKIAFA LKEQGLPLAG SQGIYQLKIG DSQRTPRVPS DDSTSEYKDM DEPDMSNVNY 300
WILRFFPFLY FKSRINWFKN SSLIESILGK TRMPLDHEYY KDGKHKEDTI DLLDSEEVIK 360
DTVLEKTFLG TSLGQPWKFQ GKNAILVLAN RCGTEDGTTI FAGSSGIYKF NGKKPKGSQD 420
DDESSLDSLN ESVELLGNLG KGLEGAILRE VQFEVFR 457 |
Gene Ontology | GO:0005739; C:mitochondrion; IDA:SGD. GO:0008418; F:protein-N-terminal asparagine amidohydrolase activity; IDA:SGD. GO:0070773; F:protein-N-terminal glutamine amidohydrolase activity; IDA:SGD. GO:0006464; P:cellular protein modification process; IMP:SGD. GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro. GO:0030163; P:protein catabolic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |