UniProt Accession

 RRAS2_MOUSE; P62071; P17082; Q3TA79; Q8C5D1; Q9D0H6 

Genbank Protein ID

 AK011419; AK078870; AK172037; BC003871 

Genbank Nucleotide ID

 BAB27607.1; BAC37432.1; BAE42790.1; AAH03871.1 

Protein Name

 Ras-related protein R-Ras2 

Protein Synonyms/Alias

  

Gene Name

 Rras2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
106	GSFEEIYKFQRQILR	ubiquitination	[1]
128	PMILIGNKADLDHQR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. 

Sequence Annotation

 NP_BIND 21 29 GTP (By similarity).
 NP_BIND 68 72 GTP (By similarity).
 NP_BIND 127 130 GTP (By similarity).
 NP_BIND 157 159 GTP (By similarity).
 MOTIF 43 51 Effector region (By similarity).
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 186 186 Phosphoserine.
 MOD_RES 201 201 Cysteine methyl ester (By similarity).
 LIPID 199 199 S-palmitoyl cysteine (Potential).
 LIPID 201 201 S-farnesyl cysteine (By similarity).  

Keyword

 Acetylation; Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Palmitate; Phosphoprotein; Prenylation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 204 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0030335; P:positive regulation of cell migration; IGI:MGI.
 GO:0007265; P:Ras protein signal transduction; IDA:MGI. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR020849; Small_GTPase_Ras. 

Pfam

 PF00071; Ras 

SMART

 SM00173; RAS 

PROSITE

 PS51421; RAS 

PRINTS

 PR00449; RASTRNSFRMNG.