CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041606
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxiredoxin 3 
Protein Synonyms/Alias
 Thioredoxin-dependent peroxide reductase, mitochondrial 
Gene Name
 Prdx3 
Gene Synonyms/Alias
 rCG_57612 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
84AVVNGEFKELSLDDFacetylation[1]
92ELSLDDFKGKYLVLFacetylation[1]
197IDPNGVIKHLSVNDLacetylation[1]
254ASKEYFEKVHQ****acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 257 AA 
Protein Sequence
MAAAAGRLLW SSVARPASTI FRSISASTVL RPVASRRTCL TDMLWSACPQ AKFAFSTSSS 60
FHTPAVTQHA PHFKGTAVVN GEFKELSLDD FKGKYLVLFF YPLDFTFVCP TEIVAFSDKA 120
NEFHDVNCEV VAVSVDSHFS HLAWINTPRK NGGLGHMNIT LLSDLTKQIS RDYGVLLESA 180
GIALRGLFII DPNGVIKHLS VNDLPVGRSV EETLRLVKAF QFVETHGEVC PANWTPESPT 240
IKPSPTASKE YFEKVHQ 257 
Gene Ontology
 GO:0005769; C:early endosome; IEA:Compara.
 GO:0008385; C:IkappaB kinase complex; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0016209; F:antioxidant activity; IEA:InterPro.
 GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IEA:Compara.
 GO:0051920; F:peroxiredoxin activity; IEA:InterPro.
 GO:0042744; P:hydrogen peroxide catabolic process; IEA:Compara.
 GO:0001893; P:maternal placenta development; IEA:Compara.
 GO:0007005; P:mitochondrion organization; IEA:Compara.
 GO:0030099; P:myeloid cell differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0033673; P:negative regulation of kinase activity; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara. 
Interpro
 IPR000866; AhpC/TSA.
 IPR024706; Peroxiredoxin_AhpC-typ.
 IPR019479; Peroxiredoxin_C.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF10417; 1-cysPrx_C
 PF00578; AhpC-TSA 
SMART
  
PROSITE
 PS51352; THIOREDOXIN_2 
PRINTS