CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018941
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Voltage-dependent anion-selective channel 
Protein Synonyms/Alias
 DmVDAC; Porin 
Gene Name
 porin 
Gene Synonyms/Alias
 POR-1; VDAC; CG6647 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
19QARDIFSKGYNFGLWacetylation[1]
27GYNFGLWKLDLKTKTacetylation[1]
31GLWKLDLKTKTSSGIacetylation[1]
60VFGSLETKYKVKDYGacetylation[1]
64LETKYKVKDYGLTLTacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; Ion transport; Membrane; Mitochondrion; Mitochondrion outer membrane; Porin; Reference proteome; Transmembrane; Transmembrane beta strand; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 282 AA 
Protein Sequence
MAPPSYSDLG KQARDIFSKG YNFGLWKLDL KTKTSSGIEF NTAGHSNQES GKVFGSLETK 60
YKVKDYGLTL TEKWNTDNTL FTEVAVQDQL LEGLKLSLEG NFAPQSGNKN GKFKVAYGHE 120
NVKADSDVNI DLKGPLINAS AVLGYQGWLA GYQTAFDTQQ SKLTTNNFAL GYTTKDFVLH 180
TAVNDGQEFS GSIFQRTSDK LDVGVQLSWA SGTSNTKFAI GAKYQLDDDA SVRAKVNNAS 240
QVGLGYQQKL RDGVTLTLST LVDGKNFNAG GHKIGVGLEL EA 282 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005741; C:mitochondrial outer membrane; NAS:FlyBase.
 GO:0016006; C:Nebenkern; IDA:FlyBase.
 GO:0046930; C:pore complex; IEA:UniProtKB-KW.
 GO:0015288; F:porin activity; IEA:UniProtKB-KW.
 GO:0008308; F:voltage-gated anion channel activity; IDA:FlyBase.
 GO:0007602; P:phototransduction; IMP:FlyBase.
 GO:0007291; P:sperm individualization; IMP:FlyBase.
 GO:0030382; P:sperm mitochondrion organization; IMP:FlyBase. 
Interpro
 IPR023614; Porin_dom.
 IPR001925; Porin_Euk.
 IPR027246; Porin_Euk/Tom40. 
Pfam
 PF01459; Porin_3 
SMART
  
PROSITE
 PS00558; EUKARYOTIC_PORIN 
PRINTS
 PR00185; EUKARYTPORIN.