UniProt Accession

 CLDN1_HUMAN; Q9NY35; B3KQR1; D3DN36; F2Z2D9; Q502Y8; Q6UVX2; Q9BUZ9; Q9NZZ5; Q9Y4S9 

Genbank Protein ID

 AJ270952; AF161522; AV656305; AY359121; AK075367; AL080097; AC021660; CH471052; CH471052; CH471052; CH471052; BC001757; BC013610; BC022551; BC095441 

Genbank Nucleotide ID

 CAB89684.1; AAF29137.1; AAQ89479.1; BAG52123.1; CAB45709.2; EAW79856.1; EAW79857.1; EAW79859.1; EAW79860.1; AAH01757.2; AAH13610.1; AAH22551.1; AAH95441.1 

Protein Name

 Claudin domain-containing protein 1 

Protein Synonyms/Alias

 Membrane protein GENX-3745 

Gene Name

 CLDND1 

Gene Synonyms/Alias

 C3orf4; HSPC174; PSEC0054; UNQ2511/PRO6000 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	ENSSDLNKSIWDEFI	ubiquitination	[1]
62	ISDEADEKTYNDALF	ubiquitination	[1]
248	RKEYTLMKAYRVA**	ubiquitination	[2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 CARBOHYD 42 42 N-linked (GlcNAc...) (Potential).
 CARBOHYD 72 72 N-linked (GlcNAc...).  

Keyword

 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 253 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS