UniProt Accession

 SCG1_MOUSE; P16014 

Genbank Protein ID

 X53028; X51429; BC014736 

Genbank Nucleotide ID

 CAA37199.1; CAA35792.1; AAH14736.1 

Protein Name

 Secretogranin-1 

Protein Synonyms/Alias

 Chromogranin-B; CgB; Secretogranin I; SgI; CCB peptide 

Gene Name

 Chgb 

Gene Synonyms/Alias

 Scg-1; Scg1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
151	QQASKEAKIYHSEER	acetylation	[1]

Reference

 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647] 

Functional Description

 Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. 

Sequence Annotation

 MOD_RES 99 99 Phosphoserine (Potential).
 MOD_RES 100 100 Phosphoserine (Potential).
 MOD_RES 147 147 Phosphoserine (By similarity).
 MOD_RES 151 151 N6-acetyllysine.
 MOD_RES 171 171 Sulfotyrosine (Potential).
 MOD_RES 256 256 Phosphoserine (By similarity).
 MOD_RES 260 260 Phosphoserine (By similarity).
 MOD_RES 300 300 Phosphoserine (Potential).
 MOD_RES 301 301 Phosphoserine (Potential).
 MOD_RES 318 318 Phosphoserine (By similarity).
 MOD_RES 342 342 Phosphoserine (By similarity).
 MOD_RES 348 348 Sulfotyrosine (By similarity).
 MOD_RES 375 375 Phosphoserine (By similarity).
 MOD_RES 378 378 Phosphoserine (By similarity).
 MOD_RES 469 469 Sulfotyrosine (Potential).
 MOD_RES 472 472 Sulfotyrosine (Probable).
 MOD_RES 532 532 Phosphoserine (Potential).
 MOD_RES 543 543 Phosphoserine (Potential).
 MOD_RES 566 566 Sulfotyrosine (Probable).
 MOD_RES 568 568 Sulfotyrosine (Potential).
 MOD_RES 624 624 Sulfotyrosine (By similarity).
 MOD_RES 626 626 Phosphoserine (By similarity).
 CARBOHYD 115 115 O-linked (GalNAc...) (Probable).
 DISULFID 36 57 By similarity.  

Keyword

 Acetylation; Cleavage on pair of basic residues; Complete proteome; Disulfide bond; Glycoprotein; Phosphoprotein; Reference proteome; Secreted; Signal; Sulfation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 677 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0030141; C:secretory granule; IEA:Compara. 

Interpro

 IPR001819; Chromogranin_AB.
 IPR018054; Chromogranin_CS.
 IPR001990; Granin. 

Pfam

 PF01271; Granin 

SMART

  

PROSITE

 PS00422; GRANINS_1
 PS00423; GRANINS_2 

PRINTS

 PR00659; CHROMOGRANIN.