UniProt Accession

 GST26_SCHJA; P08515 

Genbank Protein ID

 M14654 

Genbank Nucleotide ID

 AAB59203.1 

Protein Name

 Glutathione S-transferase class-mu 26 kDa isozyme 

Protein Synonyms/Alias

 GST 26; Sj26 antigen; SjGST 

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Schistosoma japonicum (Blood fluke) 

NCBI Taxa ID

 6182 

Lysine Modification

Position	Peptide	Type	References
11	ILGYWKIKGLVQPTR	propionylation	[1]
11	ILGYWKIKGLVQPTR	ubiquitination	[2]
113	VSRIAYSKDFETLKV	acetylation	[3]
113	VSRIAYSKDFETLKV	ubiquitination	[2]
180	FPKLVCFKKRIEAIP	propionylation	[1]
181	PKLVCFKKRIEAIPQ	propionylation	[1]
191	EAIPQIDKYLKSSKY	ubiquitination	[2]
194	PQIDKYLKSSKYIAW	ubiquitination	[2]

Reference

 [1] Protein acyltransferase function of purified calreticulin. Part 1: characterization of propionylation of protein utilizing propoxycoumarin as the propionyl group donor.
 Singh P, Ponnan P, Krishnan S, Tyagi TK, Priya N, Bansal S, Scumaci D, Gaspari M, Cuda G, Joshi P, Gambhir JK, Saluja D, Prasad AK, Saso L, Rastogi RC, Parmar VS, Raj HG.
 J Biochem. 2010 May;147(5):625-32. [PMID: 20071373]
 [2] E3-independent ubiquitination of AtMAPR/MSBP1.
 Kao AL, Lin YH, Chen RP, Huang YY, Chen CC, Yang CC.
 Phytochemistry. 2012 Jun;78:7-19. [PMID: 22513011]
 [3] Moonlighting protein in Starkeyomyces koorchalomoides: characterization of dihydrolipoamide dehydrogenase as a protein acetyltransferase utilizing acetoxycoumarin as the acetyl group donor.
 Tyagi TK, Ponnan P, Singh P, Bansal S, Batra A, Collin F, Guillonneau F, Jore D, Patkar SA, Saxena RK, Parmar VS, Rastogi RC, Raj HG.
 Biochimie. 2009 Jul;91(7):868-75. [PMID: 19383527] 

Functional Description

 Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. 

Sequence Annotation

 DOMAIN 2 83 GST N-terminal.
 DOMAIN 85 203 GST C-terminal.
 REGION 7 8 Glutathione binding.
 REGION 41 45 Glutathione binding.
 REGION 54 55 Glutathione binding.
 REGION 67 68 Glutathione binding.
 BINDING 111 111 Substrate (Probable).  

Keyword

 3D-structure; Direct protein sequencing; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0004364; F:glutathione transferase activity; IEA:EC. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00043; GST_C
 PF02798; GST_N 

SMART

  

PROSITE

 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS