CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029146
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
 WD repeat domain phosphoinositide-interacting protein 4 
Gene Name
 WDR45 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
54DLCPSLEKQLLVFPGubiquitination[1]
123RLFDTQSKEKLVELRubiquitination[1, 2]
273KIESIGLKRTPMGLLubiquitination[1, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 292 AA 
Protein Sequence
MTQQPLRGVT SLRFNQDQSC FCCAMETGVR IYNVEPLMEK GHLGLCDLCP SLEKQLLVFP 60
GHKCGSLQLV DLASTKPGTS SAPFTINAHQ SDIACVSLNQ PGTVVASASQ KGTLIRLFDT 120
QSKEKLVELR RGTDPATLYC INFSHDSSFL CASSDKGTVH IFALKDTRLN RRSAYVRPLH 180
TLLSALVVAV ALGVLVWAAE TRAAVRRCRR SHPAACLAAV LAVGLLVLWV AGGACTFLFS 240
IAGPVLLILV HASLRLRNLK NKIENKIESI GLKRTPMGLL LEALGQEQEA GS 292 
Gene Ontology
  
Interpro
 IPR004895; Prenylated_rab_accept_PRA1.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03208; PRA1
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
  
PRINTS