| Tag | Content |
|---|
| CPLM ID | CPLM-023628 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 443 |
Protein Synonyms/Alias | Krueppel-type zinc finger protein ZK1 |
Gene Name | ZNF443 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 539 | YECKTCRKAFGHYDN | methylation | [1] |
|
Reference | [1] Large-scale global identification of protein lysine methylation in vivo. Cao XJ, Arnaudo AM, Garcia BA. Epigenetics. 2013 May 1;8(5):477-85. [ PMID: 23644510] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 4 86 KRAB.
ZN_FING 134 159 C2H2-type 1; degenerate.
ZN_FING 169 191 C2H2-type 2; degenerate.
ZN_FING 197 219 C2H2-type 3.
ZN_FING 225 247 C2H2-type 4.
ZN_FING 253 275 C2H2-type 5.
ZN_FING 281 303 C2H2-type 6.
ZN_FING 309 331 C2H2-type 7.
ZN_FING 337 359 C2H2-type 8.
ZN_FING 365 387 C2H2-type 9.
ZN_FING 393 415 C2H2-type 10.
ZN_FING 421 443 C2H2-type 11.
ZN_FING 449 471 C2H2-type 12.
ZN_FING 477 498 C2H2-type 13; degenerate.
ZN_FING 504 526 C2H2-type 14.
ZN_FING 532 554 C2H2-type 15.
ZN_FING 560 582 C2H2-type 16.
ZN_FING 588 610 C2H2-type 17.
ZN_FING 616 638 C2H2-type 18.
ZN_FING 649 671 C2H2-type 19. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 671 AA |
Protein Sequence | MASVALEDVA VNFTREEWAL LGPCQKNLYK DVMQETIRNL DCVVMKWKDQ NIEDQYRYPR 60
KNLRCRMLER FVESKDGTQC GETSSQIQDS IVTKNTLPGV GPCESSMRGE KVMGHSSLNC 120
YIRVGAGHKP HEYHECGEKP DTHKQRGKAF SYHNSFQTHE RLHTGKKPYD CKECGKSFSS 180
LGNLQRHMAV QRGDGPYKCK LCGKAFFWPS LLHMHERTHT GEKPYECKQC SKAFSFYSSY 240
LRHERTHTGE KPYECKQCSK AFPFYSSYLR HERTHTGEKP YKCKQCSKAF PDSSSCLIHE 300
RTHTGEKPYT CKQCGKAFSV SGSLQRHETT HSAEKPYACQ QCGKAFHHLG SFQRHMIRHT 360
GNGPHKCKIC GKGFDCPSSL QSHERTHTGE KPYECKQCGK ALSHRSSFRS HMIMHTGDGP 420
HKCKVCGKAF VYPSVFQRHE RTHTAEKPYK CKQCGKAYRI SSSLRRHETT HTGEKPYKCK 480
LGKACIDFCS FQNHKTTHTG EKPYECKECG KAFSRFRYLS RHKRTHTGEK PYECKTCRKA 540
FGHYDNLKVH ERIHSGEKPY ECKECGKAFS WLTCFLRHER IHMREKSYEC PQCGKAFTHS 600
RFLQGHEKTH TGENPYECKE CGKAFASLSS LHRHKKTHWK KTHTGENPYE CKECGKAFAS 660
LSSLHRHKKT H 671 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006917; P:induction of apoptosis; TAS:ProtInc. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006950; P:response to stress; TAS:ProtInc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |