CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009917
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Spermidine/putrescine import ATP-binding protein PotA 
Protein Synonyms/Alias
  
Gene Name
 potA 
Gene Synonyms/Alias
 b1126; JW1112 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
181SLSALDYKLRKQMQNacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. 
Sequence Annotation
 DOMAIN 18 248 ABC transporter.
 NP_BIND 50 57 ATP (Potential).  
Keyword
 ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Direct protein sequencing; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 378 AA 
Protein Sequence
MGQSKKLNKQ PSSLSPLVQL AGIRKCFDGK EVIPQLDLTI NNGEFLTLLG PSGCGKTTVL 60
RLIAGLETVD SGRIMLDNED ITHVPAENRY VNTVFQSYAL FPHMTVFENV AFGLRMQKTP 120
AAEITPRVME ALRMVQLETF AQRKPHQLSG GQQQRVAIAR AVVNKPRLLL LDESLSALDY 180
KLRKQMQNEL KALQRKLGIT FVFVTHDQEE ALTMSDRIVV MRDGRIEQDG TPREIYEEPK 240
NLFVAGFIGE INMFNATVIE RLDEQRVRAN VEGRECNIYV NFAVEPGQKL HVLLRPEDLR 300
VEEINDDNHA EGLIGYVRER NYKGMTLESV VELENGKMVM VSEFFNEDDP DFDHSLDQKM 360
AINWVESWEV VLADEEHK 378 
Gene Ontology
 GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IDA:EcoCyc.
 GO:0015417; F:polyamine-transporting ATPase activity; IMP:EcoCyc.
 GO:0015594; F:putrescine-importing ATPase activity; IEA:InterPro.
 GO:0015595; F:spermidine-importing ATPase activity; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR017879; ABC_Sperm/Put_ATP-bd_PotA.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR008995; Mo/tungstate-bd_C_term_dom.
 IPR027417; P-loop_NTPase.
 IPR005893; Sp_pt_ABC_ATP-bd.
 IPR013611; Transp-assoc_OB_typ2. 
Pfam
 PF00005; ABC_tran
 PF08402; TOBE_2 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2
 PS51305; POTA 
PRINTS