| Tag | Content |
|---|
| CPLM ID | CPLM-023031 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein ZFP69B |
Protein Synonyms/Alias | Zinc finger protein 643 |
Gene Name | ZFP69B |
Gene Synonyms/Alias | ZNF643 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 191 | STLGRISKCNKLESQ | ubiquitination | [1] | | 194 | GRISKCNKLESQQEN | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 74 145 KRAB.
ZN_FING 279 301 C2H2-type 1.
ZN_FING 307 329 C2H2-type 2.
ZN_FING 335 357 C2H2-type 3.
ZN_FING 363 385 C2H2-type 4.
ZN_FING 391 413 C2H2-type 5.
ZN_FING 419 441 C2H2-type 6.
ZN_FING 447 469 C2H2-type 7.
ZN_FING 475 497 C2H2-type 8.
ZN_FING 503 525 C2H2-type 9. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 534 AA |
Protein Sequence | MLQQLLITLP TEASTWVKLR HPKAATERVA LWEDVTKMFK AEALLSQDAD ETQGESLESR 60
VTLGSLTAES QELLTFKDVS VDFTQEEWGQ LAPAHRNLYR EVMLENYGNL VSVGCQLSKP 120
GVISQLEKGE EPWLMERDIS GVPSSDLKSK TKTKESALQN DISWEELHCG LMMERFTKGS 180
SMYSTLGRIS KCNKLESQQE NQRMGKGQIP LMCKKTFTQE RGQESNRFEK RINVKSEVMP 240
GPIGLPRKRD RKYDTPGKRS RYNIDLVNHS RSYTKMKTFE CNICEKIFKQ LIHLTEHMRI 300
HTGEKPFRCK ECGKAFSQSS SLIPHQRIHT GEKPYECKEC GKTFRHPSSL TQHVRIHTGE 360
KPYECRVCEK AFSQSIGLIQ HLRTHVREKP FTCKDCGKAF FQIRHLRQHE IIHTGVKPYI 420
CNVCSKTFSH STYLTQHQRT HTGERPYKCK ECGKAFSQRI HLSIHQRVHT GVKPYECSHC 480
GKAFRHDSSF AKHQRIHTGE KPYDCNECGK AFSCSSSLIR HCKTHLRNTF SNVV 534 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |