CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029003
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ca2+-dependent activator protein for secretion 2 isoform b 
Protein Synonyms/Alias
  
Gene Name
 Cadps2 
Gene Synonyms/Alias
 CAPS2b 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
289GRLQLAEKMAKERRFubiquitination[1]
930DTLLCNGKFHKHLQEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1304 AA 
Protein Sequence
MLDPSSSEEE SDEGLEEESR EVLVAPGVSQ RAPPAAAREG RRDAPGRSGG GSGGGAARPV 60
SPSPSVLSEG RNEPELQLDE EQERRIRLQL YVFVVRCIAY PFNAKQPTDM ARRQQKLNKQ 120
QLQLLKERFQ AFLNGETQIV ADEAFCNAVR SYYEVFLKSD RVARMVQSGG CSANDFREVF 180
KKNIEKRVRS LPEIDGLSKE TVLSSWIAKY DAIYRGEEDL CKQPNRMTLS AVSELILSKE 240
QLYEMFQQIL GIKKLEHQLL YNACQLDNAD EQAAQIRREL DGRLQLAEKM AKERRFPRFI 300
SKEMESMYIE ELRASVNLLM ANLESLPVSK GGPEFKLQKL KRSQNSAFLD LGDENEIQLS 360
KSDVVLSFTL EIVIMEVQGL KSVAPNRIVY CTMEVEGGEK LQTDQAEASR PQWGTQGDFN 420
TTHPRPVVKV KLFTESTGVL ALEDKELGRV VLYPTSNSSK SAELHRMTVP KNSQDSDLKI 480
KLAVRMDKPA HMKHSGYLYA LGQKVWKRWK KRYFVLVQVS QYTFAMCSYR EKKSEPQELM 540
QLEGYTVDYT DPHPGLQGGQ VFFNAVKEGD TVIFASDDEQ DRILWVQAMY RATGQSYKPV 600
PAVQSQKLNP KGGALHADAQ LYADRFQKHG MDEFISASPC KLDHAFLFRI LQRQTLDHRL 660
NDSYSCLGWF SPGQVFVLDE YCARYGVRGC HRHLCYLTEL MEHSENGAVI DPTLLHYSFA 720
FCASHVHGNR PDGIGTVSVE EKERFEEIKD RLSSLLENQI SHFRYCFPFG RPEGALKATL 780
SLLERVLMKD IATPIPAEEV KKVVRKCLEK AALINYTRLT EYAKIEGPAE KETETMNQAT 840
PARKLEEVLH LAELCIEVLQ QNEEHHAEGR EAFAWWPDLL AEHAEKFWAL FTVDMDTALE 900
AQPQDSWDSF PLFQLLNNFL RNDTLLCNGK FHKHLQEIFV PLVVRYVDLM ESAIAQSIHR 960
GFEQETWQPV KNIANSLPNV ALPKVPSLPL NLPQIPSFST PPWMASLYES TNGSTTSEDL 1020
FWKLDALQMF VFDLHWPEQE FAHHLEQRLK LMASDMIEAC VKRTRTAFEL KLQKANKTTD 1080
LRIPASVCTM FNVLVDAKKQ STKLCALDGG QEQQYHSKID DLIDNTVKEI IALLVSKFVS 1140
VLEGVLSKLS RYDEGTFFSS ILSFTVKAAA KYVDVPKPGM DLADTYIMFV RQNQDILREK 1200
VNEEMYIEKL FDQWYSNSMK VICVWLADRL DLQLHIYQLK TLIKIVKKTY RDFRLQGVLE 1260
GTLNSKTYDT LHRRLTVEEA TASVSEGGGL QGITMKDSDE EEEG 1304 
Gene Ontology
 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.
 GO:0045211; C:postsynaptic membrane; IDA:MGI.
 GO:0042734; C:presynaptic membrane; IDA:MGI.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0045921; P:positive regulation of exocytosis; IDA:MGI.
 GO:0016082; P:synaptic vesicle priming; IGI:MGI. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR010439; Ca-dep_secretion_activator.
 IPR014770; Munc13_1.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF06292; DUF1041 
SMART
 SM00239; C2
 SM00233; PH 
PROSITE
 PS51258; MHD1
 PS50003; PH_DOMAIN 
PRINTS