CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016186
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetratricopeptide repeat protein 7B 
Protein Synonyms/Alias
 TPR repeat protein 7B; Tetratricopeptide repeat protein 7-like-1; TPR repeat protein 7-like-1 
Gene Name
 TTC7B 
Gene Synonyms/Alias
 TTC7L1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
785GRYSLAEKILRDAVQubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
 REPEAT 97 131 TPR 1.
 REPEAT 219 252 TPR 2.
 REPEAT 363 396 TPR 3.
 REPEAT 397 430 TPR 4.
 REPEAT 479 514 TPR 5.
 REPEAT 516 548 TPR 6.
 REPEAT 549 582 TPR 7.
 REPEAT 696 729 TPR 8.
 REPEAT 730 763 TPR 9.
 REPEAT 765 797 TPR 10.
 REPEAT 798 831 TPR 11.
 MOD_RES 673 673 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 843 AA 
Protein Sequence
MATKKAGSRL ETEIERCRSE CQWERIPELV KQLSAKLIAN DDMAELLLGE SKLEQYLKEH 60
PLRQGASPRG PKPQLTEVRK HLTAALDRGN LKSEFLQESN LIMAKLNYVE GDYKEALNIY 120
ARVGLDDLPL TAVPPYRLRV IAEAYATKGL CLEKLPISSS TSNLHVDREQ DVITCYEKAG 180
DIALLYLQEI ERVILSNIQN RSPKPGPAPH DQELGFFLET GLQRAHVLYF KNGNLTRGVG 240
RFRELLRAVE TRTTQNLRMT IARQLAEILL RGMCEQSYWN PLEDPPCQSP LDDPLRKGAN 300
TKTYTLTRRA RVYSGENIFC PQENTEEALL LLLISESMAN RDAVLSRIPE HKSDRLISLQ 360
SASVVYDLLT IALGRRGQYE MLSECLERAM KFAFEEFHLW YQFALSLMAA GKSARAVKVL 420
KECIRLKPDD ATIPLLAAKL CMGSLHWLEE AEKFAKTVVD VGEKTSEFKA KGYLALGLTY 480
SLQATDASLR GMQEVLQRKA LLAFQRAHSL SPTDHQAAFY LALQLAISRQ IPEALGYVRQ 540
ALQLQGDDAN SLHLLALLLS AQKHYHDALN IIDMALSEYP ENFILLFSKV KLQSLCRGPD 600
EALLTCKHML QIWKSCYNLT NPSDSGRGSS LLDRTIADRR QLNTITLPDF SDPETGSVHA 660
TSVAASRVEQ ALSEVASSLQ SSAPKQGPLH PWMTLAQIWL HAAEVYIGIG KPAEATACTQ 720
EAANLFPMSH NVLYMRGQIA ELRGSMDEAR RWYEEALAIS PTHVKSMQRL ALILHQLGRY 780
SLAEKILRDA VQVNSTAHEV WNGLGEVLQA QGNDAAATEC FLTALELEAS SPAVPFTIIP 840
RVL 843 
Gene Ontology
  
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2.
 IPR019734; TPR_repeat.
 IPR026900; Ttc7. 
Pfam
 PF07719; TPR_2
 PF13181; TPR_8 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS