UniProt Accession

 ANXA7_HUMAN; P20073; Q5F2H3; Q5T0M6; Q5T0M7 

Genbank Protein ID

 J04543; AB062429; BT007187; CR407686; AL512656; AL353731; AL512656; AL353731; AL353731; AL353731; AL512656; AL353731; AL512656; CH471083; CH471083; BC002632 

Genbank Nucleotide ID

 AAA36616.1; BAB93492.1; AAP35851.1; CAG28614.1; CAI15290.1; CAI15290.1; CAI15291.1; CAI15291.1; CAI52483.1; CAI52484.1; CAI52484.1; CAI52485.1; CAI52485.1; EAW54493.1; EAW54494.1; AAH02632.1 

Protein Name

 Annexin A7 

Protein Synonyms/Alias

 Annexin VII; Annexin-7; Synexin 

Gene Name

 ANXA7 

Gene Synonyms/Alias

 ANX7; SNX; OK/SW-cl.95 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
177	EILRKAMKGFGTDEQ	ubiquitination	[1]
408	ERLYYAMKGAGTDDS	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. 

Sequence Annotation

 REPEAT 5 9 1.
 REPEAT 10 14 2.
 REPEAT 16 20 3.
 REPEAT 189 254 Annexin 1.
 REPEAT 266 326 Annexin 2.
 REPEAT 349 409 Annexin 3.
 REPEAT 425 485 Annexin 4.
 REGION 1 143 Repeat-rich region.
 REGION 5 20 3 X 5 AA tandem repeats of G-Y-P-P-X.
 MOD_RES 233 233 N6-acetyllysine.  

Keyword

 Acetylation; Alternative splicing; Annexin; Calcium; Calcium/phospholipid-binding; Complete proteome; Direct protein sequencing; Polymorphism; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 488 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IDA:BHF-UCL.
 GO:0005635; C:nuclear envelope; IEA:Compara.
 GO:0005634; C:nucleus; IDA:BHF-UCL.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0031982; C:vesicle; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0006874; P:cellular calcium ion homeostasis; IEA:Compara.
 GO:0009992; P:cellular water homeostasis; IEA:Compara.
 GO:0007599; P:hemostasis; IEA:Compara.
 GO:0008360; P:regulation of cell shape; IEA:Compara.
 GO:0009651; P:response to salt stress; IEA:Compara.
 GO:0035176; P:social behavior; IEP:UniProtKB. 

Interpro

 IPR001464; Annexin.
 IPR018502; Annexin_repeat.
 IPR018252; Annexin_repeat_CS.
 IPR013286; AnnexinVII. 

Pfam

 PF00191; Annexin 

SMART

 SM00335; ANX 

PROSITE

 PS00223; ANNEXIN 

PRINTS

 PR00196; ANNEXIN.
 PR01871; ANNEXINVII.