| Tag | Content |
|---|
| CPLM ID | CPLM-005607 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable serine/threonine-protein kinase COQ8, mitochondrial |
Protein Synonyms/Alias | Activity of bc1 complex protein 1; Coenzyme Q protein 8; Ubiquinone biosynthesis protein COQ8 |
Gene Name | COQ8 |
Gene Synonyms/Alias | ABC1; YGL119W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 251 | PKGLFLDKTIANART | acetylation | [1] | | 275 | REARALQKFEALLKD | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Putative protein kinase involved in the biosynthesis of coenzyme Q. Affects the molecular organization and function of COQ3, probably through kinase activity towards COQ3. |
Sequence Annotation | DOMAIN 188 501 Protein kinase.
NP_BIND 194 202 ATP (By similarity).
ACT_SITE 346 346 Proton acceptor (By similarity).
BINDING 216 216 ATP (By similarity). |
Keyword | ATP-binding; Complete proteome; Kinase; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase; Transit peptide; Ubiquinone biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 501 AA |
Protein Sequence | MVTNMVKLRN LRRLYCSSRL LRTIQNGRIS SVSSISLSKK YTTKSAKEGE ENVERKHEEE 60
KKDTLKSSSV PTSRISRLFH YGSLAAGVGM NAAAKGISEV AKGNSPTWKS LILSDSNIDR 120
ITNKFSKMRG VALKIGQLLS FQDEKVLPKE LYEILSRVQN SANHMPQRQL EKVMAKELGA 180
NWKTKFSKFD KIPMAAASIG QVHAAELPSG QRVVVKIQYP GVKESIDSDL NSLLMLLTAS 240
SLLPKGLFLD KTIANARTEL KWECDYNREA RALQKFEALL KDDPAFEVPH VFPEYTTDNI 300
ITMTRMEGTE IMKLPKASQE TKNFISENIM RLCLEEIATF KYMQTDPNWA NFLYNGRTKK 360
IELLDFGASR PFAEDFILKY RKLLTYATLR DRKGAYEMSV QLGYLTGLES QSMKDAHVDS 420
VLTLGEPFRG DVDKSFDFKD QTVSDRIRGN IGLMLNERLC PPPEETYSLH RKFSGIFLLC 480
ARMGASVHCA KLFKEIFAYK V 501 |
Gene Ontology | GO:0031314; C:extrinsic to mitochondrial inner membrane; IDA:SGD. GO:0005759; C:mitochondrial matrix; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004672; F:protein kinase activity; IMP:SGD. GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. GO:0009060; P:aerobic respiration; IMP:SGD. GO:0006744; P:ubiquinone biosynthetic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |