CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027127
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protease serine 2 isoform B 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
254YNYVDWIKDTIAANSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Hydrolase; Protease; Serine protease. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MHMRETSGFT LKKGRSAPLV FHPPDALIAA PFDDDDKIVG GYICEENSVP YQVSLNSGYH 60
FCGGSLISEQ WVVSAGHCYK SRIQVRLGEH NIEVLEGNEQ FINAAKIIRH PKYNSRTLDN 120
DILLIKLSSP AVINSRVSAI SLPTAPPAAG TESLISGWGN TLSSGADYPD ELQCLDAPVL 180
SQAECEASYP GKITNNMFCV GFLEGGKDSC QGDSGGPVVS NGELQGIVSW GYGCAQKNRP 240
GVYTKVYNYV DWIKDTIAAN S 261 
Gene Ontology
 GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001254; Peptidase_S1.
 IPR018114; Peptidase_S1_AS.
 IPR001314; Peptidase_S1A.
 IPR009003; Trypsin-like_Pept_dom. 
Pfam
 PF00089; Trypsin 
SMART
 SM00020; Tryp_SPc 
PROSITE
 PS50240; TRYPSIN_DOM
 PS00134; TRYPSIN_HIS
 PS00135; TRYPSIN_SER 
PRINTS
 PR00722; CHYMOTRYPSIN.