CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019459
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 68 
Protein Synonyms/Alias
  
Gene Name
 TMEM68 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
81YKRKNVLKEAYSHNLubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 324 AA 
Protein Sequence
MIDKNQTCGV GQDSVPYMIC LIHILEEWFG VEQLEDYLNF ANYLLWVFTP LILLILPYFT 60
IFLLYLTIIF LHIYKRKNVL KEAYSHNLWD GARKTVATLW DGHAAVWHGY EVHGMEKIPE 120
DGPALIIFYH GAIPIDFYYF MAKIFIHKGR TCRVVADHFV FKIPGFSLLL DVFCALHGPR 180
EKCVEILRSG HLLAISPGGV REALISDETY NIVWGHRRGF AQVAIDAKVP IIPMFTQNIR 240
EGFRSLGGTR LFRWLYEKFR YPFAPMYGGF PVKLRTYLGD PIPYDPQITA EELAEKTKNA 300
VQALIDKHQR IPGNIMSALL ERFH 324 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro. 
Interpro
 IPR002123; Plipid/glycerol_acylTrfase. 
Pfam
 PF01553; Acyltransferase 
SMART
 SM00563; PlsC 
PROSITE
  
PRINTS