| Tag | Content |
|---|
| CPLM ID | CPLM-015295 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein aurora borealis |
Protein Synonyms/Alias | HsBora |
Gene Name | BORA |
Gene Synonyms/Alias | C13orf34 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 106 | AIEEFFTKDVIVPSP | ubiquitination | [1] | | 260 | PIQASAKKYSLGSIT | ubiquitination | [1] | | 538 | KSQAFNMKQDHTTQR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Required for the activation of AURKA at the onset of mitosis. |
Sequence Annotation | MOD_RES 183 183 Phosphoserine.
MOD_RES 270 270 Phosphoserine. |
Keyword | Cell cycle; Cell division; Complete proteome; Mitosis; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 559 AA |
Protein Sequence | MGDVKESKMQ ITPETPGRIP VLNPFESPSD YSNLHEQTLA SPSVFKSTKL PTPGKFRWSI 60
DQLAVINPVE IDPEDIHRQA LYLSHSRIDK DVEDKRQKAI EEFFTKDVIV PSPWTDHEGK 120
QLSQCHSSKC TNINSDSPVG KKLTIHSEKS DAACQTLLSL PVDFNLENIL GDYFRADEFA 180
DQSPGNLSSS SLRRKLFLDG NGSISDSLPS ASPGSPHSGV QTSLEMFYSI DLSPVKCRSP 240
LQTPSSGQFS SSPIQASAKK YSLGSITSPS PISSPTFSPI EFQIGETPLS EQRKFTVHSP 300
DASSGTNSNG ITNPCIRSPY IDGCSPIKNW SPMRLQMYSG GTQYRTSVIQ IPFTLETQGE 360
DEEDKENIPS TDVSSPAMDA AGIHLRQFSN EASTHGTHLV VTAMSVTQNQ SSASEKELAL 420
LQDVEREKDN NTVDMVDPIE IADETTWIKE PVDNGSLPMT DFVSGIAFSI ENSHMCMSPL 480
AESSVIPCES SNIQMDSGYN TQNCGSNIMD TVGAESYCKE SDAQTCEVES KSQAFNMKQD 540
HTTQRCWMKT ASPFQCSSP 559 |
Gene Ontology | GO:0051301; P:cell division; IEA:UniProtKB-KW. GO:0007067; P:mitosis; IEA:UniProtKB-KW. GO:0007088; P:regulation of mitosis; IMP:UniProtKB. GO:0060236; P:regulation of mitotic spindle organization; IMP:UniProtKB. GO:0032880; P:regulation of protein localization; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |