UniProt Accession

 EIF1B_HUMAN; O60739; Q9UQF8 

Genbank Protein ID

 AF064607; AF077052; AF263452; BC006996 

Genbank Nucleotide ID

 AAC17112.1; AAD27785.1; AAF79182.1; AAH06996.1 

Protein Name

 Eukaryotic translation initiation factor 1b 

Protein Synonyms/Alias

 eIF1b; Protein translation factor SUI1 homolog GC20 

Gene Name

 EIF1B 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
42	IQQRNGRKTLTTVQG	ubiquitination	[1]
58	ADDYDKKKLVKAFKK	acetylation	[2]
61	YDKKKLVKAFKKKFA	acetylation	[2]
91	QLQGDQRKNICQFLL	ubiquitination	[3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931] 

Functional Description

 Probably involved in translation. 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 9 9 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Initiation factor; Phosphoprotein; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 113 AA 

Protein Sequence

Gene Ontology

 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
 GO:0006446; P:regulation of translational initiation; NAS:UniProtKB. 

Interpro

 IPR005874; SUI1_euk.
 IPR001950; TIF_SUI1. 

Pfam

 PF01253; SUI1 

SMART

  

PROSITE

 PS50296; SUI1 

PRINTS