UniProt Accession

 PCNA_DROME; P17917; Q540V1; Q9V909 

Genbank Protein ID

 M33950; AE013599; AE013599; AY122197 

Genbank Nucleotide ID

 AAA28746.1; AAF57493.1; AAS64796.1; AAM52709.1 

Protein Name

 Proliferating cell nuclear antigen 

Protein Synonyms/Alias

 PCNA; Cyclin; Mutagen-sensitive 209 protein 

Gene Name

 mus209 

Gene Synonyms/Alias

 PCNA; CG9193 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
59	LRSDGFDKFRCDRNL	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. 

Sequence Annotation

 DNA_BIND 61 80 Potential.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; DNA replication; DNA-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 260 AA 

Protein Sequence

Gene Ontology

 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043626; C:PCNA complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
 GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.
 GO:0006261; P:DNA-dependent DNA replication; TAS:FlyBase.
 GO:0007307; P:eggshell chorion gene amplification; TAS:FlyBase.
 GO:0006298; P:mismatch repair; TAS:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0006289; P:nucleotide-excision repair; TAS:FlyBase.
 GO:0006275; P:regulation of DNA replication; IEA:InterPro. 

Interpro

 IPR000730; Pr_cel_nuc_antig.
 IPR022649; Pr_cel_nuc_antig_C.
 IPR022659; Pr_cel_nuc_antig_CS.
 IPR022648; Pr_cel_nuc_antig_N. 

Pfam

 PF02747; PCNA_C
 PF00705; PCNA_N 

SMART

  

PROSITE

 PS01251; PCNA_1
 PS00293; PCNA_2 

PRINTS

 PR00339; PCNACYCLIN.