CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015373
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Atherin 
Protein Synonyms/Alias
 Sterile alpha motif domain-containing protein 1; SAM domain-containing protein 1 
Gene Name
 SAMD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
75RTRAELEKLIQQRAVubiquitination[1]
88AVLRVSYKGSISYRNubiquitination[1]
378QSAKERVKEWTPCGPubiquitination[1]
514IRLGPALKIYEHHIKubiquitination[1]
521KIYEHHIKVLQQGHFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May play a role in atherogenesis by immobilizing LDL in the atherial wall. 
Sequence Annotation
 DOMAIN 462 530 SAM.
 MOD_RES 161 161 Phosphoserine.
 MOD_RES 261 261 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Polymorphism; Reference proteome; Secreted. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 538 AA 
Protein Sequence
MAGPPALPPP ETAAAATTAA AASSSAASPH YQEWILDTID SLRSRKARPD LERICRMVRR 60
RHGPEPERTR AELEKLIQQR AVLRVSYKGS ISYRNAARVQ PPRRGATPPA PPRAPRGAPA 120
AAAAAAPPPT PAPPPPPAPV AAAAPARAPR AAAAAATAPP SPGPAQPGPR AQRAAPLAAP 180
PPAPAAPPAV APPAGPRRAP PPAVAAREPP LPPPPQPPAP PQQQQPPPPQ PQPPPEGGAV 240
RAGGAARPVS LREVVRYLGG SGGAGGRLTR GRVQGLLEEE AAARGRLERT RLGALALPRG 300
DRPGRAPPAA SARPSRSKRG GEERVLEKEE EEDDDEDEDE EDDVSEGSEV PESDRPAGAQ 360
HHQLNGERGP QSAKERVKEW TPCGPHQGQD EGRGPAPGSG TRQVFSMAAM NKEGGTASVA 420
TGPDSPSPVP LPPGKPALPG ADGTPFGCPP GRKEKPSDPV EWTVMDVVEY FTEAGFPEQA 480
TAFQEQEIDG KSLLLMQRTD VLTGLSIRLG PALKIYEHHI KVLQQGHFED DDPDGFLG 538 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. 
Interpro
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1. 
Pfam
 PF00536; SAM_1 
SMART
 SM00454; SAM 
PROSITE
 PS50105; SAM_DOMAIN 
PRINTS