UniProt Accession

 E9PKT6_HUMAN; E9PKT6 

Genbank Protein ID

 AC011944 

Genbank Nucleotide ID

  

Protein Name

 Cathepsin H 

Protein Synonyms/Alias

  

Gene Name

 CTSH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
30	PQNCSATKSNYLRGT	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 134 AA 

Protein Sequence

Gene Ontology

 GO:0001669; C:acrosomal vesicle; IEA:Compara.
 GO:0001520; C:outer dense fiber; IEA:Compara.
 GO:0004177; F:aminopeptidase activity; IEA:Compara.
 GO:0016505; F:apoptotic protease activator activity; IEA:Compara.
 GO:0004197; F:cysteine-type endopeptidase activity; IEA:Compara.
 GO:0004252; F:serine-type endopeptidase activity; IEA:Compara.
 GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Compara.
 GO:0060448; P:dichotomous subdivision of terminal units involved in lung branching; IEA:Compara.
 GO:0033619; P:membrane protein proteolysis; IEA:Compara.
 GO:0001656; P:metanephros development; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0045766; P:positive regulation of angiogenesis; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0010634; P:positive regulation of epithelial cell migration; IEA:Compara.
 GO:0031648; P:protein destabilization; IEA:Compara.
 GO:0032526; P:response to retinoic acid; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara.
 GO:0001913; P:T cell mediated cytotoxicity; IEA:Compara.
 GO:0031638; P:zymogen activation; IEA:Compara. 

Interpro

 IPR000169; Pept_cys_AS.
 IPR013128; Peptidase_C1A.
 IPR000668; Peptidase_C1A_C. 

Pfam

 PF00112; Peptidase_C1 

SMART

  

PROSITE

 PS00139; THIOL_PROTEASE_CYS 

PRINTS