UniProt Accession

 RECX_ECOLI; P33596; P77798 

Genbank Protein ID

 L25853; U00096; AP009048 

Genbank Nucleotide ID

 AAA19106.1; AAC75740.1; BAA16560.1 

Protein Name

 Regulatory protein RecX 

Protein Synonyms/Alias

 Protein OraA 

Gene Name

 recX 

Gene Synonyms/Alias

 oraA; b2698; JW2668 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
140	LPTVFSEKVKIQRFL	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Modulates RecA activity through direct physical interaction. Can inhibit both RecA recombinase and coprotease activities. May have a regulatory role during the SOS response. Inhibits DNA strand exchange in vitro. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; DNA damage; DNA repair; Reference proteome; SOS response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
 GO:0006282; P:regulation of DNA repair; IDA:EcoCyc.
 GO:0006974; P:response to DNA damage stimulus; IMP:EcoCyc.
 GO:0009432; P:SOS response; IEA:UniProtKB-KW. 

Interpro

 IPR003783; Regulatory_RecX.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF02631; RecX 

SMART

  

PROSITE

  

PRINTS