CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein YfiQ 
Protein Synonyms/Alias
  
Gene Name
 yfiQ 
Gene Synonyms/Alias
 b2584; JW2568 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
23AVIGASMKPNRAGYLacetylation[1]
200DYLARDSKTSAILLYacetylation[1]
397VKHHPRSKYVSLLTNacetylation[1]
721LEEWVELKNGERCLFacetylation[1]
748QFISRVTKEDLYYRYacetylation[1]
819VLVRSDLKGLGLGRRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 487 523 ATP-grasp.
 DOMAIN 726 881 N-acetyltransferase.  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 886 AA 
Protein Sequence
MSQRGLEALL RPKSIAVIGA SMKPNRAGYL MMRNLLAGGF NGPVLPVTPA WKAVLGVLAW 60
PDIASLPFTP DLAVLCTNAS RNLALLEELG EKGCKTCIIL SAPASQHEDL RACALRHNMR 120
LLGPNSLGLL APWQGLNASF SPVPIKRGKL AFISQSAAVS NTILDWAQQR KMGFSYFIAL 180
GDSLDIDVDE LLDYLARDSK TSAILLYLEQ LSDARRFVSA ARSASRNKPI LVIKSGRSPA 240
AQRLLNTTAG MDPAWDAAIQ RAGLLRVQDT HELFSAVETL SHMRPLRGDR LMIISNGAAP 300
AALALDALWS RNGKLATLSE ETCQKLRDAL PEHVAISNPL DLRDDASSEH YIKTLDILLH 360
SQDFDALMVI HSPSAAAPAT ESAQVLIEAV KHHPRSKYVS LLTNWCGEHS SQEARRLFSE 420
AGLPTYRTPE GTITAFMHMV EYRRNQKQLR ETPALPSNLT SNTAEAHLLL QQAIAEGATS 480
LDTHEVQPIL QAYGMNTLPT WIASDSTEAV HIAEQIGYPV ALKLRSPDIP HKSEVQGVML 540
YLRTANEVQQ AANAIFDRVK MAWPQARVHG LLVQSMANRA GAQELRVVVE HDPVFGPLIM 600
LGEGGVEWRP EDQAVVALPP LNMNLARYLV IQGIKSKKIR ARSALRPLDV AGLSQLLVQV 660
SNLIVDCPEI QRLDIHPLLA SGSEFTALDV TLDISPFEGD NESRLAVRPY PHQLEEWVEL 720
KNGERCLFRP ILPEDEPQLQ QFISRVTKED LYYRYFSEIN EFTHEDLANM TQIDYDREMA 780
FVAVRRIDQT EEILGVTRAI SDPDNIDAEF AVLVRSDLKG LGLGRRLMEK LITYTRDHGL 840
QRLNGITMPN NRGMVALARK LGFNVDIQLE EGIVGLTLNL AQREES 886 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0048037; F:cofactor binding; IEA:InterPro.
 GO:0004468; F:lysine N-acetyltransferase activity; IMP:EcoliWiki.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0052858; F:peptidyl-lysine N-acetyltransferase activity; IDA:EcoCyc.
 GO:0018393; P:internal peptidyl-lysine acetylation; IDA:EcoCyc.
 GO:0009408; P:response to heat; IMP:EcoCyc.
 GO:0006979; P:response to oxidative stress; IMP:EcoCyc. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR011761; ATP-grasp.
 IPR013816; ATP_grasp_subdomain_2.
 IPR003781; CoA-bd.
 IPR000182; GNAT_dom.
 IPR016040; NAD(P)-bd_dom.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF00583; Acetyltransf_1
 PF13380; CoA_binding_2 
SMART
 SM00881; CoA_binding 
PROSITE
 PS50975; ATP_GRASP
 PS51186; GNAT 
PRINTS