CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycylpeptide N-tetradecanoyltransferase 
Protein Synonyms/Alias
  
Gene Name
 NMT2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
478ALILAKSKGFDVFNAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). 
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 529 AA 
Protein Sequence
MAEDSESAAS QQSLELDDQD TCGIDGDNEE ETEHAKGSPG GYLGAKKKKK KQKRKKEKPN 60
SGGTKSDSAS DSQEIKIQQP SKHNTIWQQI SAGAAMGSAT MEGEWTGMRN DHKNPSVPMQ 120
KLQDIQRAME LLSACQGPAR NIDEAAKHRY QFWDTQPVPK LDEVITSHGA IEPDKDNVRQ 180
EPYSLPQGFM WDTLDLSDAE VLKELYTLLN ENYVEDDDNM FRFDYSPEFL LWALRPPGWL 240
LQWHCGVRVS SNKKLVGFIS AIPANIRIYD SVKKMVEINF LCVHKKLRSK RVAPVLIREI 300
TRRVNLEGIF QAVYTAGVVL PKPIATCRYW HRSLNPRKLV EVKFSHLSRN MTLQRTMKLY 360
RLPDVTKTSG LRPMEPKDIK SVRELINTYL KQFHLAPVMD EEEVAHWFLP REHIIDTFVV 420
ESPNGKLTDF LSFYTLPSTV MHHPAHKSLK AAYSFYNIHT ETPLLDLMSD ALILAKSKGF 480
DVFNALDLME NKTFLEKLKF GIGDGNLQYY LYNWRCPGTD SEKVGLVLQ 529 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:EC.
 GO:0006499; P:N-terminal protein myristoylation; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000903; MyristoylCoA_TrFase.
 IPR022677; MyristoylCoA_TrFase_C.
 IPR022678; MyristoylCoA_TrFase_CS.
 IPR022676; MyristoylCoA_TrFase_N. 
Pfam
 PF01233; NMT
 PF02799; NMT_C 
SMART
  
PROSITE
 PS00975; NMT_1
 PS00976; NMT_2 
PRINTS