UniProt Accession

 HMGN4_HUMAN; O00479; B2R4I6; Q53XL9 

Genbank Protein ID

 U90549; BT009824; AK311841; AL121936; CH471087; BC001282 

Genbank Nucleotide ID

 AAB53427.1; AAP88826.1; BAG34783.1; CAC16803.1; EAW55586.1; AAH01282.1 

Protein Name

 High mobility group nucleosome-binding domain-containing protein 4 

Protein Synonyms/Alias

 Non-histone chromosomal protein HMG-17-like 3; Non-histone chromosomal protein 

Gene Name

 HMGN4 

Gene Synonyms/Alias

 HMG17L3; NHC 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	RSARLSAKPAPPKPE	ubiquitination	[1]
82	ASTLQSQKAEGTGDA	acetylation	[2, 3]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 

Functional Description

  

Sequence Annotation

 MOD_RES 80 80 Phosphoserine.
 MOD_RES 82 82 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 90 AA 

Protein Sequence

Gene Ontology

 GO:0000785; C:chromatin; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0031492; F:nucleosomal DNA binding; IEA:InterPro. 

Interpro

 IPR000079; HMGN_fam. 

Pfam

 PF01101; HMG14_17 

SMART

 SM00527; HMG17 

PROSITE

 PS00355; HMG14_17 

PRINTS

 PR00925; NONHISHMG17.